Ehiogu was 44-year-old and made his name as a player at Aston Villa, representing the Midlands club from 1991 until 2000, forming a formidable centre-back partnership with current England manager Gareth Southgate.
The former defender also went on to gain international recognition, making four appearances for England before he retired in 2009.
Ehiogu was employed by Spurs as a youth coach and took over as the under 23 mentor in 2014.
The North London club said in a statement: “It is with immense sadness that we announce the passing of Ugo Ehiogu, our Under-23 coach.
The Club sends its deepest condolences to Ugo’s family.
“His wife Gemma has specifically asked that the family are given privacy at this difficult time.
“We should also like to place on record our thanks to all the medical professionals including those at North Middlesex University Hospital, Royal Brompton Hospital and Harefield Hospital for their care and support.”
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